AllerGen Investigators

Enhancing RAP for First Nations Communities

Surveillance of occupational asthma

An Assessment of Long-Term Indoor Residential Pollution Exposures among Canadian Children ——- Better Exposure Avoidance Measures (BEAM) and New Environmental Sensor Tool Development ——- Environmental impact, inflammation and the role of IL-13 receptor a2 ——- Improved Tools for Assessing Long-Term Indoor and Outdoor Exposures in Epidemiologic Studies of Allergy and Asthma & Repeat Home Visits and Alternative Sampling Techniques in the Mini-CHILD Study (Mini-CHILD II) ——- Mini-CHILD: Assessment of the home environment ——- Mini-CHILD: Environmental assessment of molecular genetic characterization of microbes in outdoor and indoor air and dust ——- The Canadian Healthy Infant Longitudinal Development (CHILD) Study —— Project 500

The Canadian Healthy Infant Longitudinal Development (CHILD) Study

CHILD Coordinator 3-year Clinic Training Session Workshop in Manitoba ——- CHILD Executive Meeting Workshop in Toronto ——- CHILD Operating Grant ——- Development of an Evidence-based Certified Allergy Educator Program ——- Infant Inflammatory Markers and Lung Function ——- Mini-CHILD: Environmental assessment of molecular genetic characterization of microbes in outdoor and indoor air and dust ——- Technology-enabled Knowledge Translation and Mobilization ——- The Canadian Healthy Infant Longitudinal Development (CHILD) Study ——- Project 500 —— Knowledge Mobilization for the CHILD Study —— Rapid Environmental Effects on Genes: The Lens of Epigenetics (REEGLE)

Clinical Investigator Collaborative (CIC) —— Markers of Inflammation – Development and Optimization of Assays —— The Clinical Investigator Collaborative (CIC)-Allergic Asthma (AA) —— The Clinical Investigator Collaborative (CIC)-Severe Asthma —— Nasal allergen challenge – reproducibility of biomarkers and effect of topical steroid treatment

Development of an Adaptive Immune Phenotyping Monitoring Platform

Gender-related biologic and sociologic impact of obesity

The Canadian Asthma Primary Prevention Study: home environment at the 14-year assessment

Postpartum Distress and Childhood Asthma: The Genetics, and the Social and Ethical Impacts of this Genetic Association

An Integrative Multidimensional Genomic and Epigenomic Approach for the Study of Short-Term Diesel Exhaust on Asthmatics ——- Allergic asthma: Air pollution and allergen interactions ——- Better Exposure Avoidance Measures (BEAM) and New Environmental Sensor Tool Development ——- Cardiopulmonary consequences of air pollution in a murine model of allergic asthma ——- Environmental Affects on Allergic Airway Disease ——- Environmental impact, inflammation and the role of IL-13 receptor a2 ——- Mini-CHILD: Environmental assessment of molecular genetic characterization of microbes in outdoor and indoor air and dust ——- Rapid Environmental Effects on Genes: The Lens of Epigenetics (REEGLE) ——- Strengthening the Case for Ongoing Reduction of Exposure to Traffic-Related Air Pollution (SCORE-TRAP) ——- The Canadian Healthy Infant Longitudinal Development (CHILD) Study ——- Workplace sensitizers: skin and lung exposure, responses and prevention

The Canadian Healthy Infant Longitudinal Development (CHILD) Study

Identification of genetic predictors of peanut allergy ——- Predicting Peanut Allergy

Stress allostatic load and risk of allergies and asthma in children of immigrants

Expression of interest proposal for strategic initiatives funding for the First Canada-China Symposium on Asthma/Allergy and Airway Smooth Muscle

Regulation of lung mucosal immune responses by heterologous exposure to multiple infectious and allergic agents —— The Clinical Investigator Collaborative (CIC)-Severe Asthma

The Canadian Healthy Infant Longitudinal Development (CHILD) Study —— Project 500

Development of an Evidence-based Certified Allergy Educator Program ——- Evaluation of the Implementation and Effectiveness of Statutory and Regulatory Based Policies for Anaphylaxis Risk Reduction —— Food Allergy Management at University from the Perspective of Students and Food Service Management

Expression of interest proposal for strategic initiatives funding for the First Canada-China Symposium on Asthma/Allergy and Airway Smooth Muscle

Engaging Aboriginal families affected by allergies and asthma in support-education program development ——-Building continuity of support for allergic children with asthma and/or anaphylaxis and their families ——- Enhancing RAP for First Nations Communities ——- Promoting Health Equity for Vulnerable Populations affected by Asthma and Allergies ——- Respiratory health awareness community outreach and engagement of First Nations community in Alberta: Pilot Intervention ——- Sustainable Online Support for Children and Adolescents Affected by Asthma and Allergies ——- The development, implementation and evaluation of strategies to promote well-being of children and youth with allergies and/or asthma (Part 2 THEME B – Improving Food Labelling for Allergens to Build Consumer Capacity)

Mini-CHILD: Development of objective measurement of airway inflammation and lung function in infants ——- An Assessment of Long-Term Indoor Residential Pollution Exposures among Canadian Children ——- CHILD Executive Meeting Workshop in Toronto ——- Collaboration between the CHILD Study and START study ——- Improved Tools for Assessing Long-Term Indoor and Outdoor Exposures in Epidemiologic Studies of Allergy and Asthma & Repeat Home Visits and Alternative Sampling Techniques in the Mini-CHILD Study (Mini-CHILD II) ——- Infant Inflammatory Markers and Lung Function ——- Mini-CHILD: Assessment of the home environment ——- Respiratory syncytial virus in the development of infant wheezing disorders: a bench to bedside approach to gene-virus interactions ——- Strategies for enhancing tolerance induction: Preclinical studies and CHILD linked project development ——- The Canadian Healthy Infant Longitudinal Development (CHILD) Study —— Stem Cell Team for Emerging BioMarkers —— Project 500 —— Knowledge Mobilization for the CHILD Study —— Rapid Environmental Effects on Genes: The Lens of Epigenetics (REEGLE)

Cardiopulmonary consequences of air pollution in a murine model of allergic asthma

Metabolomics ——- Non-invasive diagnosis: Metabolics for the various phenotypes of asthma (formerly: Diagnosing the Various Phenotypes of Asthma: The Use of Urine NMR) ——- Urine NMR-based Metabolomics for Asthma Diagnosis

Mini-CHILD: Assessment of the home environment ——- An Assessment of Long-Term Indoor Residential Pollution Exposures among Canadian Children ——- Better Exposure Avoidance Measures (BEAM) and New Environmental Sensor Tool Development ——- Development of a Human Phthalate Inhalation Exposure Model ——- Do indoor exposures to phthalates act independently or as an adjuvant in the development of inflammation and allergic disease? ——- Improved Tools for Assessing Long-Term Indoor and Outdoor Exposures in Epidemiologic Studies of Allergy and Asthma & Repeat Home Visits and Alternative Sampling Techniques in the Mini-CHILD Study (Mini-CHILD II) ——- Mini-CHILD: Environmental assessment of molecular genetic characterization of microbes in outdoor and indoor air and dust ——- Phthalate Exposure in Canadian Children during the First Three Years of Life ——- Rapid Environmental Effects on Genes: The Lens of Epigenetics (REEGLE) ——- The Canadian Healthy Infant Longitudinal Development (CHILD) Study ——- Chemical Management Program (CMP) Investment in Analayis of CHILD Urine Samples for Metabolites of Phthalates —— Project 500

Respiratory syncytial virus in the development of infant wheezing disorders: a bench to bedside approach to gene-virus interactions ——- The Canadian Healthy Infant Longitudinal Development (CHILD) Study

Allergic asthma: Air pollution and allergen interactions ——- Changing Practice for Prevention and Early Detection of Occupational Asthma and Allergic Diseases in the Primary Care Setting ——- Workplace sensitizers: skin and lung exposure, responses and prevention ——- Work-Related Asthma and Allergy: Prevention and Early Detection (WRAAPED) research program

Gender-related biologic and sociologic impact of obesity

An Integrative Multidimensional Genomic and Epigenomic Approach for the Study of Short-Term Diesel Exhaust on Asthmatics ——- Allergic Asthma functional & Pharmaco-genomics for Early and Late Phase Response Biomarkers ——- Clinical Investigator Collaborative (CIC) ——- Development of a Microarray Genotyping Chip for Clinical Trials ——- Functional genetics in allergy ——- Functional genomic and proteomic changes in response to nasal allergen challenge and following peptide immunotherapy treatment of the same: A partnership with the Allergic-Rhinitis Clinical Investigator Collaborative (AR-CIC) and industry ——- Genetics of the early and late responses to AllerGen challenge ——- Mini-CHILD: AllerChip – Development, Validation and Implementation of a Microarray Genotyping Tool for Allergy and Asthma Research ——- Pharmacogenetics & Genetic Testing 3D graphical animation tool —— Predictive Biomarkers of the Late-Phase Response —— Markers of Inflammation – Development and Optimization of Assays —— The Clinical Investigator Collaborative (CIC)-Allergic Asthma (AA) —— Strengthening the Case for Ongoing Reduction of Exposure to Traffic-Related Air Pollution (SCORE-TRAP) —— Biomarker development for monitoring responses in CIC clinical trials

Development of national strategies for implementing and evaluating evidence-based indicators for benchmarking and monitoring asthma care in Canada ——- Antenatal steroid therapy for fetal lung maturation: Is there an association with childhood asthma ——- Can e-health tools improve health outcomes in asthma? ——- Changing Practice for Prevention and Early Detection of Occupational Asthma and Allergic Diseases in the Primary Care Setting ——- Enhancing RAP for First Nations Communities ——- Promoting Health Equity for Vulnerable Populations affected by Asthma and Allergies ——- The Canadian Healthy Infant Longitudinal Development (CHILD) Study ——- The Respiratory Global Research And Training (GREAT) Network ——- Work-Related Asthma and Allergy: Prevention and Early Detection (WRAAPED) research program

Ontogeny and genetic polymorphisms of the innate immune system intersecting in asthma ——- CHILD Executive Meeting Workshop in Toronto ——- Development of an Adaptive Immune Phenotyping Monitoring Platform ——- Expansion of existing capacity of immunology platform to support Canadian Healthy Infant Longitudinal Development study (birth cohort) ——- Functional genetics in allergy ——- Knowledge Mobilization Cafe Scientifique on the top of allergies (food and drug) ——- Mini-CHILD: Assessment of the home environment ——- Mini-CHILD: Recruitment ——- Rapid Environmental Effects on Genes: The Lens of Epigenetics (REEGLE) ——- Respiratory syncytial virus in the development of infant wheezing disorders: a bench to bedside approach to gene-virus interactions ——- The Canadian Healthy Infant Longitudinal Development (CHILD) Study —— Pre-commercialization studies to develop a microbiota-based diagnostic and preventative for asthma —— Stem Cell Team for Emerging BioMarkers —— Project 500 —— Strengthening the Case for Ongoing Reduction of Exposure to Traffic-Related Air Pollution (SCORE-TRAP) —— Knowledge Mobilization for the CHILD Study —— Let Them Eat Dirt: The Hunt for Our Kids’ Missing Microbes

Financial barriers to medication use in children with asthma: Effect on health outcomes ——- Parental preferences for asthma control in children ——- Pharmacogenetics & Genetic Testing 3D graphical animation tool

Mini-CHILD: Environmental assessment of molecular genetic characterization of microbes in outdoor and indoor air and dust

Canadian Group of Food Allergy Research (CanGoFAR) ——- Canadian Group on Food Allergy Research (CanGoFAR) ——- Disease Management: Canadian peanut thresholds study

Allergic asthma: Air pollution and allergen interactions ——- Development of a Human Phthalate Inhalation Exposure Model ——- Environmental impact on the epithelial immune barrier in asthma

Evaluation of the Implementation and Effectiveness of Statutory and Regulatory Based Policies for Anaphylaxis Risk Reduction

Clinical Investigator Collaborative (CIC) ——- Metabolomics ——- Non-invasive diagnosis: Metabolics for the various phenotypes of asthma (formerly: Diagnosing the Various Phenotypes of Asthma: The Use of Urine NMR) ——- Proposed Severe Asthma Network —— Urine Metabolomics Analysis for Asthma Diagnosis

Allergic Rhinitis Clinical Investigator Collaborative (AR-CIC): Development of a standardized nasal allergen challenge model for a multi-center research collaborative to investigate novel therapeutic agents for allergic rhinitis ——- Developmental plasticity and fetal programming of asthma in mice ——- The Clinical Investigator Collaborative (CIC)-Allergic Rhinitis (AR) ——- Urine NMR-based Metabolomics for Asthma Diagnosis —— Urine Metabolomics Analysis for Asthma Diagnosis —— Improved diagnosis of asthma: metabolomics

Cardiopulmonary consequences of air pollution in a murine model of allergic asthma

Predicting Peanut Allergy ——- A Cross-Canada Anaphylaxis Registry (C-CARE) ——- Allergic Rhinitis Clinical Investigator Collaborative (AR-CIC): Development of a standardized nasal allergen challenge model for a multi-center research collaborative to investigate novel therapeutic agents for allergic rhinitis ——- Canadian Group of Food Allergy Research (CanGoFAR) ——- Canadian Group on Food Allergy Research (CanGoFAR) ——- Certified Allergy Educator Program ——- Cross-Canada Anaphylaxis REgistry (C-CARE) ——- Development of an Adaptive Immune Phenotyping Monitoring Platform ——- Development of an Evidence-based Certified Allergy Educator Program ——- Disease Management: Canadian peanut thresholds study ——- Disease Modulation Clinical Tolerance Study ——- Evaluation of the Implementation and Effectiveness of Statutory and Regulatory Based Policies for Anaphylaxis Risk Reduction ——- Identification of genetic predictors of peanut allergy ——- Mobilizing best practices in Asthma and Allergy management and use of the Air Quality Health Index in the Canadian sport and recreation community ——- Stress allostatic load and risk of allergies and asthma in children of immigrants ——- Technology-enabled Knowledge Translation and Mobilization ——- The Clinical Investigator Collaborative (CIC)-Allergic Rhinitis (AR) ——- The development, implementation and evaluation of strategies to promote well-being of children and youth with allergies and/or asthma (Part 2 THEME B – Improving Food Labelling for Allergens to Build Consumer Capacity) ——- The distribution and function of FceR1 on nerves ——- Development of a National Food Allergy Strategy for Canada: Step 1 —— Stock Epinephrine in Hamilton Food Courts —— Engaging Knowledge Users: Usability Testing of a Canadian Anaphylaxis Emergency Plan —— Prevention and management of adverse reactions to food in schools—a systematic review and practice guidelines —— Investigation of Strategies to Dismantle Persistent Peanut Allergy —— Food Allergy Management at University from the Perspective of Students and Food Service Management

Canadian Group of Food Allergy Research (CanGoFAR) ——- Canadian Group on Food Allergy Research (CanGoFAR) ——- Disease Management: Canadian peanut thresholds study ——- Disease Modulation Clinical Tolerance Study ——- Functional consequences of innate immune receptor polymorphisms

Building continuity of support for allergic children with asthma and/or anaphylaxis and their families

Better Exposure Avoidance Measures (BEAM) and New Environmental Sensor Tool Development ——- Improved Tools for Assessing Long-Term Indoor and Outdoor Exposures in Epidemiologic Studies of Allergy and Asthma & Repeat Home Visits and Alternative Sampling Techniques in the Mini-CHILD Study (Mini-CHILD II) ——- Phthalate Exposure in Canadian Children during the First Three Years of Life ——- Chemical Management Program (CMP) Investment in Analayis of CHILD Urine Samples for Metabolites of Phthalates

Development of a Microarray Genotyping Chip for Clinical Trials ——- Mini-CHILD: AllerChip – Development, Validation and Implementation of a Microarray Genotyping Tool for Allergy and Asthma Research ——- Neuroendocrine Regulation of Allergic Inflammation: Translational Studies

SPAACE Surveying Prevalence of food Allergies in All Canadian Environments ——- Surveying the Prevalence of food Allergy in All Canadian Environments -Trends Over Time (SPAACE to SPAACE)

The Canadian Asthma Primary Prevention Study: home environment at the 14-year assessment

Allergy-Brain Connection (ABC) Research Team

Regulation of lung mucosal immune responses by heterologous exposure to multiple infectious and allergic agents

Development of a Microarray Genotyping Chip for Clinical Trials ——- Mini-CHILD: AllerChip – Development, Validation and Implementation of a Microarray Genotyping Tool for Allergy and Asthma Research

Environmental Affects on Allergic Airway Disease