CHILD Publications

Refereed Journal Articles

The database below lists the refereed journal articles that have emerged from the Canadian Healthy Infant Longitudinal Development (CHILD) Study.

The database can be sorted and/or searched by different data fields. When searching by author, use last name only.

Author(s)	Year	Title	Journal
Kang LJ, Kolevaa PT, Field CJ, Giesbrecht GF, Wine E, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR, Scott JA, Kozyrskyj AL, and CHILD Study Investigators	2018	Maternal depressive symptoms linked to reduced fecal Immunoglobulin A concentrations in infants	Brain, Behavior, and Immunity
Dharma C, Lefebvre DL, Tran MM, Lou WYW, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Sears MR, the CHILD Study investigators	2018	Patterns of allergic sensitization and atopic dermatitis from 1 to 3 years: effects on allergic diseases	Clinical & Experimental Allergy
Kamal M, Tamana S, Smithson L, Ding L, Lau A, Chikuma J, Mariasine J, Lefebvre DL, Subbarao P, Becker AB, Turvey SE, Sears MR, CHILD Study investigators, Pei J, Mandhane PJ	2018	Phenotypes of sleep disordered breathing symptoms to 2 years of age based on age of onset and duration of symptoms	Sleep Medicine
Smithson L, Baird T, Tamana S, Lau A, Mariasine J, Chikuma J, Lefebvre DL, Subbarao P, Becker AB, Turvey SE, Sears MR, CHILD Study investigators, Beal D, Pei J, Mandhane PJ.	2018	Shorter sleep duration is associated with reduced cognitive development at 2 years of age	Sleep Medicine
Forbes JD, Azad MB Vehling L, Tun HM, Konya TB, Guttman DS, Field CJ, Lefebvre D, Sears MR, Becker AB, Mandhane PJ, Tuvey SE, Mores TJ, Subbarao P, Scott JA, Kozyrskyj AL	2018	Formula exposure in hospital and subsequent feeding practices: associations with gut microbiota and overweight risk in the first year of life	JAMA Pediatrics
Entz R, Rai U, Rycroft J, Chari RS, Kozyrskyj AL	2018	Regional caesarean delivery practices, the maternal-infant microbiome, and risk for asthma	Journal of Obstetrics Gyneacology Canada
Lu Z, Foong R, Kowalik K, Moraes TJ, Dubeau A, Balkovec S, Gustafsson PM, Becker AB, Mandhane PJ, Turvey SE, Lou W, Ratjen F, Sears M, Subbarao P	2018	Ventilation inhomogeneity in infants with recurrent wheezing	Thorax
Lu Z, Foong R, Kowalik K, Moraes TJ, Dubeau A, Lefebvre D, Davis S, Balkovec S, Becker A, Mandhane P, Turvey S, Lou W, Sears MR, Ratjen F, Subbarao P	2018	Reference equations for the interpretation of forced expiratory and plethysmographic measurements in infants	Pediatric Pulmonology
Bridgman SL, Azad MB, Persaud RR, Chari RS, Becker AB, Sears MR, Mandhane PJ, Turvey SE, Subbarao P, Haqq AM, Kozyrskyj AL	2018	Impact of maternal pre-pregnancy overweight on infant overweight at 1 year of age: associations and sex-specific differences	Pediatric Obstetrics
Miliku K, Robertson B, Sharma AK, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Lefebvre DL, Sears MR, the CHILD Study Investigators, Bode L, Azad M.	2018	Human milk oligosaccharides and food sensitization among infants in the CHILD Study	Allergy
Tun HM, Bridgman SL, Chari R, Field CJ, Guttman DS, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR, Scott JA, Kozyrskyj AL	2018	Roles of Birth Mode and Infant Gut Microbiota in Intergenerational Transmission of Overweight and Obesity From Mother to Offspring	JAMA Pediatrics
Vehling L, Chan D, McGavock J, Becker AB, Subbarao P, Moraes TJ, Mandhane PJ, Turvey SE, Lefebvre DL, Sears MR, Azad MB	2018	Exclusive breastfeeding in hospital predicts longer breastfeeding duration in Canada: Implications for health equity	Birth Journal
Tran MM, Sears MR	2018	Can the atopic march be predicted?	Annals of Allergy, Asthma & Immunology
Graham C, Chooniedass R, Stefura WP, Lotoski L, Lopez P, Befus AD, Becker AB, HayGlass KT.	2017	Stability of pro- and anti-inflammatory immune biomarkers for human cohort studies	Journal of Translational Medicine
Van der leek AP, Yanishevskyj Y, Kozyrskyj AL.	2017	The Kynurenine Pathway As a Novel Link between Allergy and the Gut Microbiome	Frontiers in Immunology
Reynolds LA, Finlay BB.	2017	Early life factors that affect allergy development	Nature Reviews Immunology
Stiemsma LT, Turvey SE	2017	Asthma and the microbiome: defining the critical window in early life	Allergy, Asthma & Clinical Immunology
Stearns JC, Zulyniak MA, de Souza RJ, Campbell NC, Fontes M, Shaikh M, Sears MR, Becker MB, Mandhane PJ, Subbarao P, Turvey SE, Gupta M, Beyene J, Surette MG, Anand SS for the NutriGen Alliance	2017	Ethnic and diet-related differences in the healthy infant microbiome	Genome Research
Bridgman SL, Azad MB, Field CJ, Haqq AM, Becker AB, Mandhane PJ, Subbarao P, Turvey SE, Sears MR, Scott JA, Wishart DS, Kozyrskyj AL, CHILD Study Investigators.	2017	Fecal Short-Chain Fatty Acid Variations by Breastfeeding Status in Infants at 4 Months: Differences in Relative versus Absolute Concentrations	Frontiers in Nutrition
Azad M, Vehling L, Lu Z, Dai D, Subbarao P, Becker AB, Mandhane PJ, Turvey S, Lefebrve DL, Sears MR, CHILD Study Investigators.	2017	Breastfeeding, maternal asthma, and wheezing in the first year of life: a longitudinal birth cohort study	European Respiratory Journal
Tran MM, Lefebvre DL, Dai D, Dharma C, Subbarao P, Lou W, Azad MB, Becker AB, Mandhane PJ, Turvey SE, Sears MR, the CHILD Study Investigators	2017	Timing of food introduction and development of food sensitization in a prospective birth cohort	Pediatric Allergy and Immunology
Tun HM, Konya T, Takaro TK, Brook JR, Chari R, Field CJ, Guttman DS, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR, Scott JA, Kozyrskyj AL, CHILD Study Investigators	2017	Exposure to household furry pets influences the gut microbiota of infant at 3-4 months following various birth scenarios	Microbiome
Graham C, Chooniedass R, Stefura WP, Becker AB, Sears MR, Turvey SE, Mandhane PJ, Subbarao P, CHILD Study Investigators , HayGlass KT.	2017	In vivo immune signatures of healthy human pregnancy: Inherently inflammatory or anti-inflammatory?	PLoS ONE
Zulyniak M, de Souza R, Mateen S, Desai,D, Lefebvre D, Gupta M, Wilson J, Wahl G, Subbarao P, Becker A, Mandhane P, Turvey S, Beyene J, Atkinson S, Morrison K, McDonald S, Koon T, Sears M, Anand S.	2017	Does the impact of a plant-based diet during pregnancy on birth weight differ by ethnicity? A dietary pattern analysis from a prospective Canadian birth cohort alliance	BMJ Open
Yasmin F, Tun HM, Konya TB, Guttman DS, Chari CJ, Becker A, Mandhane PJ, Turvey SE, Subbarao P, Sears MR, Scott JA, Dinu I, Kozyrskyj A	2017	Cesarean section, formula feeding and infant antibiotic exposure: separate and combined impacts on gut microbial changes in later infancy	Frontiers in Pediatrics, Neonatology
Tamana S, Smithson L, Lau A, Mariasine J, Young R, Chikuma J, Lefebvre DL, Subbarao P, Becker AB, Turvey SE, Sears MR, CHILD Study investigators, Pei J, Mandhane PJ	2017	Parent-Reported Symptoms of Sleep-Disordered Breathing Are Associated With Increased Behavioral Problems at 2 Years of Age: The Canadian Healthy Infant Longitudinal Development Birth Cohort Study	SLEEP
Chan D, Goruk S, Becker A, Subbarao P, Mandhane P, Turvey S, Lefebvre D, Sears M, CHILD Study investigators, Field C, Azad M	2017	Adiponectin, leptin and insulin in breastmilk: associations with maternal characteristics and infant body composition in the first year of life	International Journal of Obesity
Tran MM, Lefebvre DL, Dharma C, Dai D, Lou WYW, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Sears MR, and the CHILD Study investigators	2017	Predicting the atopic march: results from the Canadian Healthy Infant Longitudinal Development Study	Journal of Allergy and Clinical Immunology
Kovela P, Tun H, Konya T, Guttman D, Becker A, Mandhane PJ, Turvey S, Sears M, Subbarao P, Scott J, Kozyrskyj A	2017	Sex-specific impact of asthma during pregnancy on infant gut microbiota	European Respiratory Journal
Klopp A, Vehling L, Becker AB, Subbarao P, Mandhane PJ, Turvey SE, Lefebvre DL, Sears MR, the CHILD Study investigators, Azad MB	2017	Modes of infant feeding and the risk of childhood asthma: a prospective birth cohort study	Journal of Pediatrics
Arrieta MC, Arevalo A, Stiemsma LT, Dimitriu PA, Chico ME, Loor S, Vaca M, Boutin RCT, Morien E, Mingliang J, Turvey SE, Walter J, Wegener Parfrey L, Cooper P, Finlay BB	2017	Associations between infant fungal and bacterial dysbiosis and childhood atopic wheeze in a nonindustrialized setting	Journal of Allergy and Clinical Immunology
Boutin RCT, Finlay BB.	2016	Microbiota-Mediated Immunomodulation and Asthma: Current and Future Perspectives	Current Treatment Options in Allergy
Arrieta MC, Sadarangani M, Brown EM, Russell SL, Nimmo M, Dean J, Turvey SE, Chan ES, Finlay BB	2016	A humanized microbiota mouse model of ovalbumin-induced lung inflammation	Gut Microbes
Arrieta MC, Walter J, Finlay BB	2016	Human Microbiota-Associated Mice: A Model with Challenges	Cell Host & Microbe
Yurist-Dousch S, Arrieta MC, Tupin A, Valdez Y, Antunes LC, Yen R, Finlay BB	2016	Nutrient Deprivation Affects Salmonella Invasion and Its Interaction with the Gastrointestinal Microbiota	PLoS ONE
de Souza RJ, Zulyniak MA, Desai D, Shaikh MR, Campbell NC, Lefebvre DL, Gupta M, Wilson J, Wahi G, Atkinson SA, Teo KK, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Sears MR, Anand SS for the NutriGen Alliance Investigators	2016	Harmonization of Food-Frequency Questionnaires and Dietary Pattern Analysis in 4 Ethnically Diverse Birth Cohorts	The Journal of Nutrition
Bridgman SL, Konya T, Azad MB, Sears MR, Becker AB, Turvey SE, Mandhane PJ, Subbarao P, CHILD Study investigators, Scott JA, Field CJ, Kozyrskyj AL	2016	Infant gut immunity: a preliminary study of IgA associations with breastfeeding	Journal of Developmental Origins Health and Disease
Subbarao P, Lu Z, Kowalik K, Brown M, Balkovec S, Gustafsson P, Lou W, Ratjen F	2016	Changes in multiple breath washout measures after raised volume rapid thoracoabdominal compression maneuvers in infants	Pediatric Pulmonology
Kozyrskyj AL, Kalu R, Koleva, PT, Bridgman SL	2016	Fetal programming of overweight through the microbiome: boys are disproportionately affected	Journal Developmental Origins Health and Disease
Sarah L. Bridgman, Konya T, Azad MB, Guttman DS, Sears MS, Becker AB, Turvey SE, Mandhane PJ, Subbarao P, CHILD Study Investigators, Scott JA, Field CJ, Kozyrskyj AL.	2016	*High fecal IgA is associated with reduced Clostridium difficile* colonization in infants**	Microbes and Infection
Stiemsma L, Arrieta MC, Dimitriu P, Cheng J, Thorson L, Lefebvre D, Azad MB, Subbarao P, Mandhane P, Becker A, Sears M, Kollmann T, Mohn W, Finlay B, Turvey S.	2016	Shifts in Lachnospira and Clostridium sp. In the 3-month stool microbiome are associated with preschool-age asthma	Clinical Science
Pakpour S, Scott JA, Turvey SE, Brook JR, Takaro TK, Sears MR, Klironomos J	2016	Presence of Archaea in the indoor environment and their relationship with housing characteristics	Microbial Ecology
Bolduc FV, Lau A, Rosenfelt CS, Langer S, Wang N, Smithson L, Lefebvre D, Alexander RT, Dickson CT, Li L, Becker AB, Subbarao P, Turvey SE, Pei J, Sears MR, Mandhane PJ	2016	Cognitive enhancement in infants associated with maternal fruit intake during pregnancy: results from a birth cohort study with validation in an animal model	EBio Medicine
Azad MB, Sharma AK, de Souza R, Dolinsky VW, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Lefebvre DL, Sears MR and the CHILD Study investigators	2016	Association Between Artificially Sweetened Beverage Consumption During Pregnancy and Infant Body Mass Index	JAMA Pediatrics
Subbarao P, Sears M and the CHILD Study investigators	2015	The Canadian Healthy Infant Longitudinal Development (CHILD) Study: examining developmental origins of allergy and asthma	Thorax
Arrieta M-C, Stiemsma LT, Dimitrui PA, Thorson L, Russell S, Yurist-Doutsch S, Mandhane P, Becker A, McNagny KM, Sears MR, Kollmann T, CHILD Study Investigators, Mohn WW, Turvey SE, Finlay BB.	2015	Early infancy microbial and metabolic alterations in children impact risk of asthma	Science Translational Medicine
Azad MB, Konya T, Guttman DS, Charie RS, Field CJ, Sears MR, Mandhane PJ, Turvey SE, Subbarao P, Becker AB, Scott JA, Kozyrskyj AL, CHILD Study Investigators.	2015	Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study	BJOG: An International Journal of Obstetrics and Gynaecology
Moraes T, Lefebvre DL, Chooniedass R, Becker AB, Brook JR, Denburg J, HayGlass KT, Hegele RG, Kollmann TR, Macri J, Mandhane PJ, Scott JA, Subbarao P, Takaro TK, Turvey SE, Duncan JD, Sears MR, Befus AD, the CHILD Study Investigators.	2015	The Canadian Healthy Infant Longitudinal Development (CHILD) Study: biological samples and biobanking	Paediatric and Perinatal Epidemiology
Azad MB, Konya T, Guttman DS, Field CJ, Sears MR, Hayglass KT, Mandhane PJ, Turvey SE, Subbarao P, Becker AB, Scott JA, Kozyrskyj AL and the CHILD study investigators	2015	Infant gut microbiota and food sensitization: associations in the first year of life	Clinical & Experimental Allergy
Takaro TK, Scott JA, Allen RW, Anand SS, Becker AB, Befus AD, Brauer M, Duncan J, Lefebvre DL, Lou W, Mandhane PJ, McLean KE, Miller G, Sbihi H, Shu H, Subbarao P, Turvey SE, Wheeler AJ, Zeng L, Sears MR, Brook JR and the CHILD study investigators	2015	The Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort study: assessment of environmental exposures	Journal of Exposure Science and Environmental Epidemiology
Sbihi H, Allen R, Becker A, Brook J, Mandhane P, Scott J, Sears M, Subbarao P, Takaro T, Turvey S, Brauer M	2015	Perinatal Exposure to Traffic-Related Air Pollution and Atopy at 1 Year of Age in a Multi-Center Canadian Birth Cohort Study	Environmental Health Perspectives
Kozyrskyj AL	2015	Can we predict future allergies from our infant gut microbiota?	Expert Review of Respiratory Medicine
Koleva PT, Kim J-S, Scott JA, Kozyrskyj AL.	2015	Microbial programming of health and disease starts during fetal life	Birth Defects Research (Part C)
Caulfield T, Burningham S, Joly Y, Master Z, Shabani M, Borry P, Becker A, Burgess M, Calder K, Critchley C, Edwards K, Fullerton SM, Gottweis H, Hyde-Lay R, Illes J, Isasi R, Kato K, Kaye J, Knoppers B, Lynch J, McGuire A, Meslin E, Nicol D, et al.	2014	A review of the key issues associated with the commercialization of biobanks	Journal of Law and Bioscience
Persaud RR, Azad MB, Chari RS, Sears MR, Becker AB, Kozyrskyj AL, the CHILD Study Investigators.	2014	Perinatal antibiotic exposure of neonates in Canada and associated risk factors: a population-based study	The Journal of Maternal-Fetal & Neonatal Medicine
Marhera A, Kahlke P, Lau A, Zeng Y, Hoskins C, Corbett T, Hemmings D, Mandhane P.	2014	You are how you recruit: a cohort and randomized controlled trial of recruitment strategies	BMC Medical Research Methods
Sbihi H, Brook JR, Allen RW, Curran J, Dell S, Mandhane P, Scott J, Sears MR, Subbarao P, Takaro T, Turvey SE, Wheeler A, Brauer M.	2013	A new exposure metric for traffic-related air pollution? An analysis of determinants of Hopanes in settled indoor house dust	Environmental Health
Konya T, Koster B, Maughan H, Escobar M, Azad MB, Guttman D, Sears MR, Becker AB, Brook JR, Takaro TK, Kozyrskyj AL, Scott JA.	2013	Associations between bacterial communities of house dust and infant gut	Environmental Research
Azad MB, Konya T, Maughan H, Guttman DS, Field CJ, Chari RS, Sears MR, Becker AB, Scott JA, Kozyrskyj AL, CHILD Study Investigators.	2013	Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months	Canadian Medical Association Journal
Azad M, Konya T, Maughan H, Guttman DS, Field CJ, Chari RS, Sears MR, Becker A, Scott JA, Kozyrskyj AL.	2013	Infant gut microbiota and the hygiene hypothesis of allergic disease: impact of household pets and siblings on microbiota composition and diversity	Allergy, Asthma & Clinical Immunology
Azad MB, Becker AB, Guttman DS, Sears MR, Scott JA, Kozyrskyj AL, on behalf of the CHILD Study Investigators	2013	Gut microbiota diversity and atopic disease: does breastfeeding play a role?	Journal of Allergy and Clinical Immunology
Lum S, Stocks J, Stanojevic S, Wade A, Robinson P, Gustafsson P, Brown M, Aurora P, Subbarao P, Hoo A-F, Sonnappa S.	2012	Age and height dependence of lung clearance index and functional residual capacity	European Respiratory Journal
Arrandale VH, Brauer M, Brook JR, Brunekreef B, Gold DR, London SJ, Miller JD, Ozkaynak H, Ries NM, Sears MR, Silverman FS, Takaro TK	2011	Exposure assessment in cohort studies of childhood asthma	Environmental Health Perspectives
Master Z, Ries N, Caulfield T.	2011	Balancing Efficiency and the Protection of Research Participants: Canadian Allergy/Asthma Researchers’ Perspectives on the Ethics Review of Multi-Site Health Research	Journal of Clinical Research and Bioethics
Ries N, LeGrandeur J, Caulfield T.	2010	Handling ethical, legal and social issues in birth cohort studies involving genetic research: responses from studies in six countries	BMC Medical Ethics
Subbarao P, Becker A, Brook JR, Daley D, Mandhane PJ, Miller GE, Turvey SE, Sears MR on behalf of the CHILD Study Investigators.	2009	Epidemiology of asthma: risk factors for development	Expert Review of Clinical Immunology
Subbarao P, Mandhane PJ, Sears MR.	2009	Asthma: epidemiology, etiology and risk factors	Canadian Medical Association Journal